VIII. Fatty Acid Activation and Transport into the
Transport and Regeneration
Fatty acyl CoA is impermeable to the inner mitochondrial membrane, so it is carried in the form of fatty acyl carnitine.
- Fatty acyl carnitine is transported across the inner
mitochondrial membrane in exchange for carnitine by an
- In the mitochondrial matrix fatty acyl carnitine reacts with
CoA in a reaction catalyzed by carnitine acyltransferase II
(CAT-II), yielding fatty acyl CoA and carnitine.
The fatty acyl CoA is now ready to undergo beta-oxidation.