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The importance of heme metabolism
	Examples of hemoproteins
	Major sites of hemoprotein synthesis
Porphyrins
	Structures of porphyrins
	Names of porphyrins
Heme synthesis
	ALA synthase
	ALA dehydratase
	Uroporphyrinogen I synthase
	Uroporphyrinogen decarboxylase
	Coproporphyrinogen III oxidase
	Protoporphyrinogen IX oxidase
	Ferrochelatase
Regulation of heme synthesis
Porphyrias
	Examples of Porphyrias
Heme degradation
	Hemoglobin
	Steps of heme degradation
	Bilirubin metabolism
	Hyperbilirubinemia
Iron metabolism overview
Iron absorption
Regulastion of iron uptake
Iron transport and storage
	Iron transport
	Iron storage

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jb

Last modified 1/5/95