This surgically treatable case of hypertension resulted from Conn's syndrome with an aldosterone secreting adenoma of the adrenal gland. The small eosinophilic laminated inclusions seen by H&E are whorls of endoplasmic reticulum by electron microscopy and represent spironolactone bodies. Studies have shown that aldosterone can be demonstrated in these bodies by immunohistochemical staining. These bodies have been described in glomerulosa-type cells of the adrenal cortex only in patients who have received spironolactone. Their presence appears unrelated to dosage or duration of treatment, but they are unlikely to be seen in patients who have discontinued spironolactone therapy more than a day prior to surgery.