Note the calcification in the media of this muscular artery. This is calcific medial sclerosis of Monckeberg, a form of arteriosclerosis seen in older persons, that does not typically have serious pathologic consequences because the arterial lumen is not compromised. Small muscular arteries in the pelvis, neck, and breast regions can be affected. These arterial calcifications can be seen in radiographs. Medial calcific sclerosis can also be seen involving the extremities in association with autonomic neuropathy in diabetes mellitus.