a = new Array(11); a[0] = "Incorrect" a[1] = "CORRECT. There is marked fatty change, or steatosis. Many hepatocytes have cytoplasm filled with a large lipid vacuole. Ethanol is a toxin that has an effect upon lipoprotein transport in hepatocytes, leading to the lipid accumulation." a[2] = "CORRECT. This is an acute myocardial infarction due to an ischemic injury in the myocardium. There is marked coagulative necrosis within the interventricular septum seen here." a[3] = "CORRECT. There is pronounced scleral icterus, consistent with hyperbilirubinemia. Hemolysis leads to increased turnover of RBC's and increased bilirubin. Metastases are unlikely to cause biliary obstruction with jaundice, because the lesions are focal, and bile can be excreted somewhere." a[4] = "CORRECT. There is a large cystic space left from the resolving liquefactive necrosis of a cerebral infarction." a[5] = "CORRECT. The black color comes from carbon pigments inhaled over the years, engulfed by macrophages, and sent via lymphatics to the nodes." a[6] = "CORRECT. Viral infections can produce single cell necrosis." a[7] = "CORRECT. The ischemia during the cardiac arrest followed by reperfusion established following successful resuscitation will generate activated oxygen species to produce free radical injury." a[8] = "CORRECT. This patient had Alzheimer's disease. Note the diffuse narrowing of gyri and widening of sulci. There is no exudate and no focal lesion." a[9] = "CORRECT. This wedge-shaped renal infarct is typically the result of an arterial thromboembolus that plugs a renal arterial branch. Such emboli usually come from a lesion in the heart." a[10] = "CORRECT. The lipochrome (lipofuscin) represents the residual debris of organelles and appears with increased frequency with aging, particularly in heart and liver." a[11] = "QUESTIONS: 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 "