Question 2

This 55 year old male presented with hypertension. Key laboratory findings include: serum cortisol at 8 am 15 microgram/dL (normal 6 - 23 microgram/dL); plasma renin activity 1.2 ng/mL/hr (normal 1.9 - 3.7 ng/mL/hr); serum aldosterone 44 ng/dL (normal 4.0 - 31.0 ng/dL); serum potassium 2.9 mmol/L (normal 3.3 - 5.0 mmol/L). The most likely diagnosis is:

A Cushing's syndrome

B Adrenal cortical carcinoma

C Multiple endocrine neoplasia, type I

D Metastatic carcinoma

E Conn's syndrome

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