A 52 year old male has required a transmetatarsal amputation a year ago. The structure identified here is not functioning adequately due to increased intracellular sorbitol concentrations. Which of the following laboratory abnormalities best explains these findings:

A Hemoglobin of 7.6 g/dL

B Calcium of 12.3 mg/dL

C Glucose of 217 mg/dL

D Antinuclear antibody titer of 1:320

E PaC02 of 60 mmHg

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