There is extensive hepatocyte necrosis seen here in a case of acetaminophen overdose. The hepatocytes at the right are dead, and those at the left are dying. This pattern can be seen with a variety of hepatotoxins. Acute liver failure leads to hepatic encephalopathy.

What gene mutation is most likely present in both sporadic and inherited forms of angiomyolipoma?

A N-acetylcysteine

B Prednisone

C Cyclophosphamide

C Pegylated interferon