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The contents of the chest and peritoneal cavity have been removed at autopsy here to reveal markedly bilaterally enlarged kidneys in the retroperitoneum in an adult who died from complications of chronic renal failure. This patient had autosomal dominant polycystic kidney disease (ADPKD). |
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On urinalysis with ADPKD, as renal failure ensues, there is loss of concentrting ability so that specific gravity resembles a filtrate of plasma at 1.010. Hemorrhage into a cyst can lead to hematuria. A small amount of albuminuria may be present. |
Macroscopic Urinalysis:
(MouseOver [or touch] below for results)
Leukocyte esterase
Nitrite
pH
Protein
Blood
Specific gravity
Ketones
Glucose
Bilirubin
| Characteristic | Result
|
|---|
| Color | Dark Yellow
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| Appearance | Cloudy
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| Leukocyte Esterase | Neg
|
| Nitrite | Neg
|
| pH | 7.5
|
| Protein | 1+
|
| Blood | 2+
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| Specific Gravity | 1.010
|
| Ketones | Neg
|
| Glucose | Neg
|
| Bilirubin | Neg
|
Microscopic Urinalysis:
| Characteristic | Result
|
|---|
| WBC/hpf | >2/hpf
|
| RBC/hpf | 50-100/hpf
|
| Casts | None
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| Other | Many oxalate crystals
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