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file:///C:/578A9DE5/John_Hurdle_files/slide0001.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" Diverse Data Mining: it’s not your mother’s database any more…
Translational Informatics
John F. Hurdle, MD, PhD
Associate Professor, Biomedical Informatics&#= 13;
Chair, Institutional Review Board = ;
University of Utah
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2
Science, v.301; pp1852-54; = 31 Mar 2006.
-What ever it is, it’s a  growth industry

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3
Translational science defined
=
•“…[to build] resources an= d develop methodologies intended to overcome blocks at both the discovery (translational between bench and bedside) and = implementation (translation between bedside and practice)…= ”
NIH CTSA RFA RM-06-001<= /span>
-Def= inition from the new NIH Roadmap vision for moving away from the old “silo” model, where a group is doing clinical research in one silo and another is doing gene sequencing (same dz) and another is doing a family-tree study = like Lisa’s in another…to an integrated enterprise

-An = attempt to speed up the efficiency of clinical research AND research spending; more = bang for the buck

-Thi= s IS the future of NIH-funded research (when you have to  push an elephant, push the way it’s leaning…)

-Wha= t’s missing: bedside back to the bench; the feedback from the Public Health perspective (e.g., Avian Flu surely is driving a lot of basic research)
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4
Translational informatics defined
• “…80% of translational science…”
JF Hurdle, InfoFair Transla= tional Informatics review, Apr 2006
-So = what is translational informatics? <click>