ROBERT P. TUCKETT

Research Associate Professor
e-mail: bob.tuckett.@m.cc.utah.edu
Web Page: http://www.utah.edu/neuropathy

Education  |  Research Interests  |  Publications





Education

B.S. University of Utah, Molecular Biology 1965
Ph.D. University of Utah, Biophysics & Bioengineering 1972


Research Interests

Dr. Tuckett’s research combines human and animal (in vitro and behavioral) models for the study of pain, peripheral nerve injury (e.g., peripheral sensory neuropathy), and pruritus. Dr. Tuckett designs and implements research protocols that involve quantitative evaluation of human sensation and performance. He is a member of the Gynecological Oncology Group’s Cancer Prevention and Control Committee (http://www.gog.org/) and participates in national clinical trials of compounds that might prevent or reverse chemotherapy-induced neuropathy, as produced by drugs such as Taxol and cisplatin, and the use of quantitative measures in Quality of Life studies. He is involved in pain research and therapeutic studies through the Pain Research Center (http://www.painresearch.utah.edu./) and in mechanisms of wrist-related repetitive motion injury through the Division of Ergonomics in the Department of Mechanical Engineering (http://www.mech.utah.edu/ergo/).

Dr. Tuckett’s animal research currently focuses on the type I (slowly adapting) mechanoreceptor complex and the modulation of its activation by neurotoxic and neurotropic agents, as well as neurogenic inflammatory substances released by activation of peripheral nociceptor (pain) endings.

Publications

Zhang, J., Huang, W., and Tuckett, R.P. (2002) C-fiber modulation of rat type I slowly adapting mechanoreceptor.  Nueroscience 115: 797-804.

He, L., Tuckett, R.P. and English, K.B. (2003) 5-HT2 and 3 receptor antagonists suppress the response of rat type I slowly adapting mechanoreceptor: an in vitro study.  Brain Res. 969: 230-236.

Ward, R., Tuckett, R., English, K., Johansson, O., and Saffle, J.R. (in press) Substance P axons and sensory threshold increase in burn-graft human skin.  J. Surg. Res.

Reese, S., Sesek, R.F., Tuckett, R.P., and Bloswisk, D.S. (in press) Measuring the effects of ergonomic risk factors on tactile sensation.  Regional NORA proc.

Sesek, R.F., Tuckett, R.P., Bloswick, D.S., and Khalighi, M. (in press) Provocative wrist flexion as an improved method for carpal tunnel syndrome screening.  Regional NORA Proc.

Sesek, R.F., Tuckett, LR.P., Bloswick, D.S., Khalighi, M., and Anderson, M. (accepted with revisions).  Effects of prolonged wrist flexion on transmission of sensory information in carpal tunnel syndrome.  J. Hand Surg. [Am].

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