Dermatology Anatomy / Physiology Clinical Abnormalities--Epidermis

Stratum corneum

John L. Bezzant, M.D.

The thick stratum corneum of the palms and soles prevents chemicals from readily entering those areas. This patient worked around a chemical to which he became allergic, and you can see the line of demarcation along the sides of his hands indicating the thinner stratum corneum on the dorsum of the hands, and a thicker stratum corneum on the palms.