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Case 1

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Question 1 Feedback -- Thyroid Stimulating Hormone

Yes, thyroid stimulating hormone is one of the correct answers.

You may investigate this further:

Clinical experience suggests thyroid disorders may result in menstrual cycle abnormalities and infertility. See this PubMed reference:

Koutras DA. Disturbances of menstruation in thyroid disease. Ann N Y Acad Sci 1997 Jun 17;816:280-284.

The menstrual disorders noted with hypothyroidism do not appear to be associated with lower levels of gonadotropins or estradiol levels. These results suggest either a decreased biological potency of the gonadotrophins or a mild ovarian resistance. See this PubMed reference:

Tomasi PA, Fanciulli G, Zini M, Demontis MA, Dettori A, Delitala G. Pulsatile gonadotrophin secretion in hypothyroid women of reproductive age. Eur J Endocrinol 1997 Apr;136(4):406-409.

When prolactin levels are elevated the measurement of TSH is essential.

See also this PubMed reference:

Natori S, Karashima T, Koga S, Abe M, Tominaga K. [A case report of idiopathic myxedema with secondary amenorrhoea and hyperprolactinemia: effect of thyroid hormone replacement on reduction of pituitary enlargement and restoration of fertility]. Fukuoka Igaku Zasshi 1991 Aug;82(8):461-463

And this PubMed reference:

Notsu K, Ito Y, Furuya H, Ohguni S, Kato Y. Incidence of hyperprolactinemia in patients with Hashimoto's thyroiditis. Endocr J 1997 Feb;44(1):89-94.

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