Question 5 of 16

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The following enzymes are involved in the catabolism of AMP to uric acid. The correct order of their use is:

1. A deaminase

2. A nucleoside phosphorylase

3. A nucleotidase

4. Xanthine oxidase

A. 1, 2, 3, 4.

B. 1, 3, 2, 4

C. 1, 4, 2, 3

D. i3, 2, 1, 4

E. 3, 1, 2, 4

Comments:

AMP is first deaminated to IMP. Then it loses the phosphate and the sugar to form the free base, hypoxanthine. Both hypoxanthine and xanthine are oxidized by xantine oxidase.

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Last modified 1/5/95