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Ovarian Malignancy Review

Of all gynecologic cancer deaths, ovarian cancer accounts for over 50%. The risk of death from ovarian cancer is 1-2%. Ovarian cancer is more common in women from northern European and North American nations than from Asian or developing nations. Risk factors include:

  • Infertility
  • Low parity
  • Use of perineal talc
  • High fat diets
  • Lactose intolerance
  • Previous breast or colon cancer
  • A family history of ovarian cancer

Unfortunately, over 2/3 of patients diagnosed with ovarian cancer have intraperitoneal metastases at the time of diagnosis. The most common malignant ovarian epithelial cancers are:

  • Serous (40-50%)
  • Endometrial (15-25%)
  • Mucinous (6-16%)
  • Clear cell (5-11%).